ELISpot Plus: Rat IL-22 (ALP)

ELISpot Plus: Rat IL-22 (ALP)

3275-4APW-2

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Components

Detection mAbMT231, biotin
Enzyme conjugateStreptavidin-ALP
SubstrateBCIP/NBT-plus
PlatePre-coated ELISpot plate, white MSIP (mAb MT230)

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Delivery 4-9 business days

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Product specifications

Intended use

This ELISpot Plus kit is intended for the enumeration of cells secreting rat IL-22 using the ELISpot assay. For research use only. Not for use in diagnostic procedures.

Serum/Plasma samples

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Product details

ProductELISpot Plus: Rat IL-22 (ALP)
ApplicationELISpot
AnalyteIL-22
ReactivityRat
SpecificityThis kit is based on a matched pair of mAbs enabling specific detection of rat IL-22.
Cross-reactivityThe mAbs react with mouse IL-22 and cross-react with IL-22 from rat. For more information please check the Cross-reactivity guide section below.

Shipping and Storage

ShippingShipped at ambient temperature.
StorageStore antibodies, enzyme conjugate, and substrate at 4-8 °C upon receipt. Plates may be kept at room temperature.
Shelf lifeAt least 18 months from date of receipt.

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IL-22

Analyte description

The cytokine interleukin 22 (IL-22) is mainly produced by activated CD4 T helper 17 (Th17) and T helper 22 (Th22) cells. The IL-22 receptor is expressed on non-immune cells, particularly epithelial cells and keratinocytes, and IL-22 promotes innate immune responses versus bacterial infections in these target cells. In addition, Th22 cells have been shown to play a role in the pathophysiology of several human skin diseases.

Alternative namesInterleukin-22, IL-22, IL22, IL-22a, ILTIFa, If2b1, Iltif
Cell typeT cell, Th1, Th17, Tfh
Gene ID50929